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Yuanmei Zhu Selected Research

Enfuvirtide (Fuzeon)

1/2020Therapeutic Efficacy and Resistance Selection of a Lipopeptide Fusion Inhibitor in Simian Immunodeficiency Virus-Infected Rhesus Macaques.
11/2019A Membrane-Anchored Short-Peptide Fusion Inhibitor Fully Protects Target Cells from Infections of Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus.
1/2019Design and Characterization of Cholesterylated Peptide HIV-1/2 Fusion Inhibitors with Extremely Potent and Long-Lasting Antiviral Activity.
1/2019Structural and functional characterization of HIV-1 cell fusion inhibitor T20.
10/2018Structural and Functional Characterization of Membrane Fusion Inhibitors with Extremely Potent Activity against Human Immunodeficiency Virus Type 1 (HIV-1), HIV-2, and Simian Immunodeficiency Virus.
1/2018Design of Novel HIV-1/2 Fusion Inhibitors with High Therapeutic Efficacy in Rhesus Monkey Models.
1/2017Enfuvirtide (T20)-Based Lipopeptide Is a Potent HIV-1 Cell Fusion Inhibitor: Implications for Viral Entry and Inhibition.

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Yuanmei Zhu Research Topics

Disease

12Infections
12/2022 - 01/2017
5Virus Diseases (Viral Diseases)
01/2020 - 01/2017
4COVID-19
12/2022 - 01/2020
2HIV Infections (HIV Infection)
01/2021 - 01/2019
2Acquired Immunodeficiency Syndrome (AIDS)
11/2020 - 11/2019
1Drug-Related Side Effects and Adverse Reactions
11/2019

Drug/Important Bio-Agent (IBA)

8Peptides (Polypeptides)IBA
12/2022 - 01/2017
7Enfuvirtide (Fuzeon)FDA Link
01/2020 - 01/2017
6LipopeptidesIBA
12/2022 - 01/2017
6Antiviral Agents (Antivirals)IBA
12/2021 - 01/2017
6Pharmaceutical PreparationsIBA
11/2020 - 01/2017
3VaccinesIBA
12/2022 - 09/2017
2Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA
12/2022 - 01/2021
2Proteins (Proteins, Gene)FDA Link
12/2022 - 11/2020
2Anti-HIV Agents (AIDS Drugs)IBA
01/2020 - 01/2019
1CholesterolIBA
12/2021
1SARS-CoV-2 spike proteinIBA
11/2020
1Polylactic Acid-Polyglycolic Acid CopolymerIBA
11/2020
1Peptide Hydrolases (Proteases)FDA Link
10/2017
1EpitopesIBA
09/2017
1Monoclonal AntibodiesIBA
09/2017

Therapy/Procedure

6Therapeutics
12/2021 - 01/2017
1Microspheres (Microsphere)
11/2020